Aegir - Skynet for Drupal - Miguel Jacq
You've probably 'heard of' Aegir - it's a hosting system for managing rapid, automated provisioning and ongoing maintenance (upgrades, cloning, destroying) of Drupal sites.
Aegir itself is made of Drupal - it consists of a Drupal frontend 'control panel' and a 'backend' which makes extensive use of Drush.