Videos tagged with Biology

A brief overview of bioinformatics computational problem landscape followed by a detailed look at one of the areas: multiple perturbation analysis of cells using reverse engineering principles. Speaker: Gary Bader Gary is Assistant Professor at the Terrence Donnelly Centre for Cellular and Biomolecular Research (CCBR) at the University of Toronto. http://baderlab.org/ Google Tech Talks August 2...

Introduced last November, the 23andMe Personal Genome Service offers customers a glimpse at their own DNA sequence, a 750-megabyte string of four characters (A, C, T and G) that functions as the operating system for a human being. Common variations in this code can influence the structure and function of the associated wetware in predictable ways. Some of these variations and their effects on t...

James D. Watson, Nobel Laureate and Chancellor of Cold Spring Harbor Laboratory, describes the years leading up to his 1953 discovery of the structure of DNA, for which he won the Nobel Prize with Drs. Francis Crick and Maurice Wilkins (1962). Dr. Watson explains that the key to uncovering the causes of brain disorders such as schizophrenia, depression, fragile X syndrome, Alzheimers, etc. is i...

In 18 months full human genome sequences will be available under $100 - and in minutes. The $5,000 full human genome was announced to come in 9 months. Is "Big IT" ready for the avalanche of data, to be obtained and processed e.g. while the patient is still on the operating table, to be diagnosed, and how the genomics glitch, that caused a benign or malign tumor, could be compensated ...

Gene regulatory networks in living cells are comprised of recurring network motifs, which perform key functions to control cellular responses. Mathematical models of network motifs are already developed and experimentally validated. We analyze the stability of previously validated mathematical models of network motifs against the fluctuations in their associated biochemical reaction rates and f...

During the lecture we will be shown the principles on which the modern development and drug discovery with emphasis on optimization of compounds with the use of three dimensional structures of the receptor. Also the use of bioinformatics will be shown and computer supported planning of ligands together with the implications of the understanding of detailed interactions between the protein and t...

It has been a century and a half since Darwin provided the first mechanistic explanation for the complexity of the living things we see around us. Only in the last 30 years or so have computational systems been employed to try out natural selection on complex artificial problems. There have been some successes, but the complexity of artificially evolved systems remains a very long way short of ...